Methylphenidate ER 72-mg tablets,
the first and only 72-mg methylphenidate ER tablet.

72 = The new 2x36 Not actual tablet image—72 is not representative of imprint. Not actual tablet size.

Methylphenidate ER 72-mg (methylphenidate HCl) extended-release tablets are a generic formulation of branded methylphenidate HCl extended-release tablets

Did you know?

In 2014, the FDA revised its guidelines for new methylphenidate ER alternatives. Methylphenidate ER 72-mg tablets met these stricter guidelines to demonstrate equivalence to branded methylphenidate HCl extended-release tablets.

Pay as little as $5 on your first prescription and as little as $15 for up to 11 refills a year*

savings copay card download & print card *Co-pay cards are available for prescription coverage assistance for qualified patients. For terms and conditions, click here. Offer void where prohibited. Other restrictions apply.

Inside each blue tablet is an osmotic (water pressure) drug-delivery system that works similarly to branded methylphenidate HCl extended-release tablets to deliver methylphenidate

  1. The immediate-release drug layer dissolves within one hour of administration 
  2. The rate-controlling semi-permeable membrane controls the rate at which water enters the tablet core
  3. The push layer in the tablet core expands and pushes drug through the laser-drilled orifice at a controlled release rate throughout the day
Methyl 72 tablet diagram

Indication and Important Safety Information

The 72-mg methylphenidate hydrochloride extended-release tablet is a prescription medication approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adolescents 13 years of age and older, and adults up to the age of 65.


See full prescribing information for complete boxed warning.

Abuse of methylphenidate may lead to dependence. Tell your healthcare professional if you or your child has had prior issues of abuse or dependence with alcohol or drugs. Keep Methylphenidate ER 72-mg tablets in a safe place to prevent misuse and abuse by others.

Who should not take Methylphenidate ER 72-mg?

Methylphenidate ER 72-mg should not be taken by patients who have:


Children under 13 years of age should not take 72-mg Methylphenidate ER tablets.

Tell your healthcare professional if you or your child has had:

Contact your healthcare professional immediately if you or your child:

Painful and prolonged erections (priapism) have occurred with methylphenidate. If you or your child develop priapism, seek medical help right away. Because of the potential for permanent damage, priapism should be evaluated by a doctor immediately.

Your child’s healthcare professional should check height and weight often and may interrupt Methylphenidate ER 72-mg treatment if your child is not growing or gaining weight as expected.

Stimulants may impair the ability of a patient to operate potentially hazardous machinery or vehicles. Caution should be used accordingly until you are reasonably certain that Methylphenidate ER 72-mg tablets do not adversely affect your or your child’s ability to engage in such activities.

The most common adverse reactions in double-blind clinical trials (>5%) reported:

Please click here for full Prescribing Information, including Boxed Warning.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.